Preheat oven to 425 degrees F. Line 2 large baking sheets with parchment paper or foil and set aside.
Scrub potatoes well and pat dry. Halve each potato lengthwise and cut into 1/2" thick wedges and sticks. Add potatoes to a large bowl and toss with olive oil, salt, and pepper to coat.
Spread potatoes in an even layer on the prepared baking sheets. Bake for 20 minutes.
While the potatoes are cooking, prepare the fish. Pat the fillets dry using a paper towel and season with salt and pepper.
Add the ingredients for the beer batter to a shallow bowl and whisk to combine. In a separate shallow bowl, combine 1/2 cup whole-wheat flour and 1/2 cup seasoned Panko breadcrumbs.
Working one at a time, dip the fish in the beer batter and gently shake off excess batter. Dredge in the breadcrumb mixture, patting the breadcrumbs to ensure that they stick.
After 20 minutes, remove the fries from the oven and flip. Push the fries to the outer edges of the baking sheets to create room in the center for the fish. Transfer 2 fish fillets to the center of each baking sheet and lightly coat both sides of the fish with cooking spray.
Return the baking sheets to the oven (depending on your oven, you may want to alternate which rack they are on to ensure even baking). Cook for an additional 10-15 minutes, until fries are golden brown and fish is crispy and flakes with a fork.** Serve warm with a squeeze of fresh lemon juice and/or tartar sauce.